Collagen clinical study

Study Design

A single-group clinical trial to evaluate the effects of Health Nag's Bioactive Collagen Jelly on skin, hair, nail, and joint health.

Conducted by:
Citruslabs, Las Vegas, USA

IRB Approval:
Yes

Study Number:
20743

Health Nag clinical studies are registered and published on ClinicalTrials.gov,
the global gold standard for clinical research transparency, operated by the U.S. National Library of Medicine (NIH).

Overview

This 12-week, virtual, single-group clinical trial assessed the effects of daily Bioactive Collagen Jelly on skin, hair, nail, joint health, and exercise recovery.

Participants

40 female participants, aged 30-55, all reporting concerns about skin health and appearance.

Product & Dosage

10 g Bioactive Collagen Jelly daily, consumed on an empty stomach each morning.

Assessments

  • Baseline (Week 0), Week 2, Week 4, Week 8, and Week 12
  • Parameters measured: Skin, Hair, Nails, Joints, and Exercise Recovery
  • Measurements included participant questionnaires (PERCEIVED), dermatologist-graded photographs (Baseline & Week 12) (DERMATOLOGIST), and clinical scoring (MEASURED)

Key

MEASURED
Definition:

Participants rated their skin, hair, nails, and joints on structured 1-5 scales (e.g. "Very poor" to "Excellent"). These ratings were converted into numerical scores and analysed as % improvements from baseline.

Examples (from questionnaire Q1-19):
  • "Nail strength improved by 69.08% in 12 weeks (measured from Q17)."
  • "Hair growth increased by 61.51% in 12 weeks (measured from Q12)."
  • "Skin hydration improved by 24.24% in just 2 weeks (measured from Q3)."
PERCEIVED / PERCEPTION / SELF REPORTED
Definition:

Participants were asked to agree or disagree with specific statements about their experience (e.g. "My skin feels more hydrated"). Results are expressed as % of participants who agreed or strongly agreed.

Examples (from questionnaire Q20-41):
  • "86.11% of participants said their skin felt more hydrated after 12 weeks (perception,
    Q20)."
  • "94.44% said they would like to continue using the product after 12 weeks
    (perception, Q39)."
  • "77.78% noticed reduced hair damage and breakage after 12 weeks (perception,
    Q27)."
  • "Nail strength improved by 69.08% in 12 weeks (measured from Q17)."
  • "Hair growth increased by 61.51% in 12 weeks (measured from Q12)."
  • "Skin hydration improved by 24.24% in just 2 weeks (measured from Q3)
DERMATOLOGIST GRADED
Definition:

Independent dermatologists reviewed participants' before-and-after photos of
skin and hair and graded visible improvements against baseline.

Examples:
  • "50% of participants showed improved overall skin health after 12 weeks
    (dermatologist graded)."
  • "68.42% showed visible improvements in hair growth (dermatologist graded)."
  • "80.95% showed reduced dandruff by Week 12 (dermatologist graded)."

Speed of Results

Within 4 Weeks
Skin
  • Measured: "Skin hydration improved by 37.79% in 4 weeks."
  • Perception: "61.54% of participants said their skin felt more hydrated after 4 weeks."
  • Measured: "Skin radiance improved by 36.75% in 4 weeks."
  • Perception: "61.54% said their skin looked more radiant after 4 weeks."
  • Perception: "74.36% agreed the product supports overall skin health by Week 4."
Hair
  • Measured: "Hair growth increased by 35.34% in 4 weeks."
  • Perception: "64.10% agreed the product supported their existing hair growth."
  • Measured: "Hair thickness improved by 32.79% in 4 weeks."
  • Measured: "Hair strength improved by 30.82% in 4 weeks."
  • Measured: "Hair loss reduced by 22.10% in 4 weeks."
  • Perception: "53.85% noticed less hair fall after 4 weeks."
Nails
  • Measured: "Nail strength improved by 48.27% in 4 weeks."
  • Perception: "61.54% reported stronger, less brittle nails after 4 weeks."
  • Perception: "61.54% reported their nails grew faster after 4 weeks."
Joints & Recovery
  • Measured: "Joint health improved by 16.55% in 4 weeks."
  • Measured: "Ability to recover after exercise improved by 17.47% in 4 weeks."
  • Perception: "58.97% agreed the product supports recovery post-exercise after 4
    weeks."
  • Perception: "51.28% said they felt less sore after exercise within 4 weeks."
  • Perception: "51.28% agreed they had less pain when exercising after 4 weeks."
Healthy Ageing
  • Perception: "66.67% agreed the product supports healthy ageing and vitality after 4 weeks.
Within 8 Weeks
Skin
  • Measured: "Skin hydration improved by 53.11% in 8 weeks."
  • Measured: "Skin radiance improved by 44.60% in 8 weeks."
  • Measured: "Evenness of skin improved by 32.63% in 8 weeks."
  • Measured: "Skin texture improved by 37.49% in 8 weeks."
  • Measured: "Skin clarity improved by 19.30% in 8 weeks."
  • Measured: "Skin firmness improved by 22.81% in 8 weeks."
  • Perception: "78.95% of participants said their skin felt more hydrated after 8 weeks."
  • Perception: "71.05% agreed their skin looked more radiant after 8 weeks."
  • Perception: *89.47% agreed the product supports overall skin health by Week 8."
Hair
  • Measured: "Hair growth increased by 50.84% in 8 weeks."
  • Measured: "Hair thickness improved by 39.61% in 8 weeks."
  • Measured: "Hair strength improved by 40.71% in 8 weeks."
  • Measured: "Hair loss reduced by 37.34% in 8 weeks."
  • Measured: "Hair thinning reduced by 34.55% in 8 weeks."
  • Perception: "81.58% agreed the product supported their existing hair growth."
  • Perception: "68.42% noticed reduced hair damage and breakage after 8 weeks."
  • Perception: "55.26% said their hair grew faster after 8 weeks."
  • Perception: "65.79% agreed their hair felt stronger after 8 weeks."
  • Perception: "63.16% noticed less hair fall after 8 weeks."
  • Perception: "55.26% reported less hair thinning after 8 weeks."
Nails
  • Measured: "Nail strength improved by 53.32% in 8 weeks."
  • Perception: "65.79% agreed their nails were stronger and less brittle after 8 weeks."
  • Perception: "65.79% reported their nails grew faster after 8 weeks."
Joints & Recovery
  • Measured: "Ability to recover after exercise improved by 22.36% in 8 weeks."
  • Measured: "Overall joint health improved by 30.14% in 8 weeks."
  • Measured: "Joint pain after walking or standing reduced by 41.52% in 8 weeks."
  • Perception: "50.00% agreed their joints were less stiff and more mobile after 8 weeks."
  • Perception: "52.63% said they felt less sore after exercise within 8 weeks."
  • Perception: "60.53% agreed the product supports recovery post-exercise after 8 weeks."
  • Perception: "52.63% reported less pain when walking long distances after 8 weeks."
Healthy Ageing
  • Perception: "84.21% agreed the product supports healthy ageing and vitality after 8 weeks."
Within 12 Weeks
Skin
  • Measured: "Skin appearance improved by 31.40% in 12 weeks."
  • Measured: "Skin hydration improved by 58.25% in 12 weeks."
  • Measured: "Skin radiance improved by 48.15% in 12 weeks."
  • Measured: "Evenness of skin improved by 32.22% in 12 weeks."
  • Measured: "Visibility of fine lines and wrinkles improved by 21.30% in 12 weeks."
  • Measured: "Skin texture improved by 43.99% in 12 weeks."
  • Measured: "Skin clarity improved by 25.00% in 12 weeks."
  • Measured: "Skin firmness improved by 32.55% in 12 weeks."
  • Perception: "86.11% of participants said their skin felt more hydrated after 12 weeks."
  • Perception: "72.22% agreed their skin looked more radiant after 12 weeks."
  • Perception: "61.11% said their skin looked more youthful after 12 weeks."
  • Perception: "88.89% agreed the product supports overall skin health by Week 12."
  • Perception: "58.33% reported their fine lines and wrinkles had noticeably reduced after 12 weeks."
Hair
  • Measured: "Overall hair health improved by 47.80% in 12 weeks."
  • Measured: "Hair growth increased by 61.51% in 12 weeks."
  • Measured: "Hair thickness improved by 48.54% in 12 weeks."
  • Measured: "Hair strength improved by 62.13% in 12 weeks."
  • Measured: "Hair loss reduced by 46.03% in 12 weeks."
  • Measured: "Hair thinning reduced by 42.03% in 12 weeks."
  • Perception: "77.78% agreed the product supported their existing hair growth."
  • Perception: "77.78% noticed reduced hair damage and breakage after 12 weeks."
  • Perception: "63.89% said their hair grew faster after 12 weeks."
  • Perception: "58.33% agreed their hair felt thicker after 12 weeks."
  • Perception: "69.44% said their hair felt stronger after 12 weeks."
  • Perception: "66.67% noticed less hair fall after 12 weeks."
  • Perception: "66.67% reported less hair thinning after 12 weeks."
Nails
  • Measured: "Nail strength improved by 69.08% in 12 weeks."
  • Perception: "75.00% agreed their nails were stronger and less brittle after 12 weeks."
  • Perception: "72.22% reported their nails grew faster after 12 weeks."
Joints & Recovery
  • Measured: "Ability to recover after exercise improved by 26.31% in 12 weeks."
  • Measured: "Overall joint health improved by 39.39% in 12 weeks."
  • Measured: "Joint pain after walking or standing reduced by 61.73% in 12 weeks."
  • Perception: "61.11% agreed their joints felt more flexible after 12 weeks."
  • Perception: "63.89% said their joints were less stiff and more mobile after 12 weeks."
  • Perception: "69.44% agreed they felt less sore after exercise within 12 weeks."
  • Perception: "69.44% agreed the product supports recovery post-exercise after 12 weeks."
  • Perception: "66.67% reported less pain when exercising after 12 weeks."
  • Perception: *72.22% said they had less pain when walking long distances after 12 weeks."
Healthy Ageing
  • Perception: "80.56% agreed the product supports healthy ageing and vitality after 12 weeks."
Continuation & Recommendation
  • Perception: "94.44% said they would like to continue using the product after 12 weeks."
  • Perception: "86.11% said they would recommend the product to family and friends.

Dermatologist Skin & Hair Grading

Clinically measured by qualified dermatologists

As part of the 12-week clinical trial, participants submitted high-resolution photographs of their face and scalp at Baseline and again at Week 12. These photos were independently reviewed and graded by a licensed dermatologist who was blinded to the study timeline.

See all Results

Skin Grading

Before Before
After After 12 Weeks
  • 79% of participants had visibly less dry skin — confirmed by a dermatologist.
  • Over half of users showed visible improvements in skin brightness, texture, and fine lines.
  • Clinically reviewed improvements in radiance, smoothness, and signs of ageing — in just 12 weeks.
  • 12 Week transformations achieved through daily bioactive collagen jelly use (10g per day).

Hair Grading

Before Before
After After 12 Weeks
  • Glowing skin, fuller hair, confirmed by an expert, not just a mirror.
  • Over 60% had shinier, fuller-looking hair – independently graded by a dermatologist.
  • Hair growth and shine improved visibly in 70% of women — according to expert review.
  • Try the collagen that visibly improved dandruff in 81% of women.

Topline Results

Key Findings

By Week 12, all 19 measured health parameters showed statistically significant improvement from baseline (p<0.05).

View Clinical Trials on ClinicalTrials.gov

Measured Clinical Gains at Week 12

+58%

More Hydrated Skin

+62%

Stronger Hair

+61%

Faster Hair Growth

+69%

Stronger Nails

+62%

Less Joint Pain

Conclusion

The Bioactive Collagen Jelly demonstrated measurable, statistically significant benefits across all 19 parameters by Week 12, with consistent improvement in skin, hair, nails, joints, and recovery.

Strongest measured improvements: nail strength, hair growth, and joint pain reduction.

Dermatologist assessments confirmed gains in skin hydration, dryness reduction, and hair health. Participant feedback reflected visible, meaningful changes in appearance and wellbeing.
These results indicate the product delivers both objective clinical improvements and noticeable user-perceived benefits in skin, hair, nail, and joint health.